Product Description

C3/C5-Depleted Serum is normal human serum in which C3 and C5 have been removed by immunoaffinity chromatography. The product is tested for the absence of C3 and C5 activity by testing classical and alternative pathway function and for the absence of C3 and C5 proteins by double immunodiffusion. The C3/C5-depleted serum is certified to exhibit less than 5% classical pathway and alternative pathway activities. Functional classical and alternative pathways can be reconstituted by addition of purified C3 protein (1.3 mg/mL) and C5 protein (75 ug/mL) indicating that all other complement components necessary for classical and alternative pathway activation are present. After reconstitution with C3 (1.3 mg C3/mL) and C5 (0.75 mg/mL), the C3/C5-Depleted Serum is certified to possess a functional classical and alternative pathway for complement activation (Morgan, B.P. (2000); Dodds, A.W. and Sim, R.B. (1997)). Although a functional lectin pathway should also be reconstituted by the addition of similar concentrations of C3 and C5, the function of this pathway is not tested.

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IBEX Technologies是一家位于蒙特利尔的公司，通过其全资子公司IBEX Pharmaceuticals Inc生产和销售用于生物医学的试剂。

该公司的产品线包括用于体外诊断和研究的高纯度酶，以及用于骨关节炎研究的ELISA试剂盒。

IBEX还向体外诊断市场的主要参与者提供定制生产服务，包括定制发酵以及一次性诊断组件的灌装和冻干。